Category: Terapia del diabete dieta e farmaci (megatrials e meta-analisi)
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N Engl J Med. 2015 Sep 17. [Epub ahead of print]

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes.

Zinman B, Wanner C, Lachin JM, Fitchett D, Bluhmki E, Hantel S, Mattheus M, Devins T, Johansen OE, Woerle HJ, Broedl UC, Inzucchi SE; EMPA-REG OUTCOME Investigators

creato: 16-11-2015 | Dimensione: 537.14 KB | Downloads: 4
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Lancet. 2005 Oct 8;366(9493):1279-89

Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial.

Dormandy JA, Charbonnel B, Eckland DJ, Erdmann E, Massi-Benedetti M, Moules IK, Skene AM, Tan MH, Lefèbvre PJ, Murray GD, Standl E, Wilcox RG, Wilhelmsen L, Betteridge J, Birkeland K, Golay A, Heine RJ, Korányi L, Laakso M, Mokán M, Norkus A, Pirags V, Podar T, Scheen A, Scherbaum W, Schernthaner G, Schmitz O, Skrha J, Smith U, Taton J; PROactive investigators.

creato: 16-11-2015 | Dimensione: 165.15 KB | Downloads: 2
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Am Heart J. 2015 May;169(5):631-638.e7.

Rationale, design, and baseline characteristics in Evaluation of LIXisenatide in Acute Coronary Syndrome, a long-term cardiovascular end point trial of lixisenatide versus placebo.

Bentley-Lewis R, Aguilar D, Riddle MC, Claggett B, Diaz R, Dickstein K, Gerstein HC, Johnston P, Køber LV, Lawson F, Lewis EF, Maggioni AP, McMurray JJ, Ping L, Probstfield JL, Solomon SD, Tardif JC, Wu Y, Pfeffer MA; ELIXA Investigators.

creato: 16-11-2015 | Dimensione: 361.54 KB | Downloads: 0
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N Engl J Med. 2015 Jul 16;373(3):232-42.

Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes.Green JB, Bethel MA, Armstrong PW, Buse JB, Engel SS, Garg J, Josse R, Kaufman KD, Koglin J, Korn S, Lachin JM, McGuire DK, Pencina MJ, Standl E, Stein PP, Suryawanshi S, Van de Werf F, Peterson ED, Holman RR; TECOS Study Group.

creato: 16-11-2015 | Dimensione: 756.11 KB | Downloads: 1
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Am Heart J. 2011 Oct;162(4):620-626.e1.

EXamination of cArdiovascular outcoMes with alogliptIN versus standard of carE in patients with type 2 diabetes mellitus and acute coronary syndrome (EXAMINE): a cardiovascular safety study of the dipeptidyl peptidase 4 inhibitor alogliptin in patients with type 2 diabetes with acute coronary syndrome

White WB, Bakris GL, Bergenstal RM, Cannon CP, Cushman WC, Fleck P, Heller S, Mehta C, Nissen SE, Perez A, Wilson C, Zannad F.

creato: 16-11-2015 | Dimensione: 224.66 KB | Downloads: 1
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N Engl J Med 359(15):1577-89. 2008

10-year follow-up of intensive glucose control in type 2 diabetes

Holman RR,Paul SK, Bethel MA, Matthews DR, Neil HA

creato: 20-01-2015 | Dimensione: 415.44 KB | Downloads: 4
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N Engl J Med 360(2):129-392009

Glucose control and vascular complications in veterans with type 2 diabetes

Duckworth W, Abraira C, Moritz T, Reda D, Emanuele N, Reaven PD, Zieve FJ, Marks J, Davis SN, Hayward R, Warren SR, Goldman S, McCarren M, Vitek ME,Henderson WG, Huang GD; VADT Investigators.

creato: 20-01-2015 | Dimensione: 573.61 KB | Downloads: 3
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N Engl J Med 12;358(24):2545-59. 2008

Effects of intensive glucose lowering in type 2 diabetes.

Action to Control Cardiovascular Risk in Diabetes Study Group, Gerstein HC, Miller ME, Byington RP, Goff DC Jr, Bigger JT, Buse JB, Cushman WC, Genuth S,Ismail-Beigi F, Grimm RH Jr, Probstfield JL, Simons-Morton DG, Friedewald WT.

creato: 20-01-2015 | Dimensione: 300.27 KB | Downloads: 1
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N Engl J Med 358(24):2560-72. 2008

Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes

ADVANCE Collaborative Group, Patel A, MacMahon S, Chalmers J, Neal B, Billot L, Woodward M, Marre M, Cooper M, Glasziou P, Grobbee D, Hamet P, Harrap S, Heller S, Liu L, Mancia G, Mogensen CE, Pan C, Poulter N, Rodgers A, Williams B, Bompoint S, de Galan BE, Joshi R, Travert F.

creato: 20-01-2015 | Dimensione: 805.55 KB | Downloads: 3
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N Engl J Med 353(25):2643-53. 2005

Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes

Nathan DM, Cleary PA, Backlund JY, Genuth SM, Lachin JM, Orchard TJ, Raskin P, Zinman B; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study Research Group.

creato: 20-01-2015 | Dimensione: 828.84 KB | Downloads: 0

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